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Podcasts Hosted by Bill Russell, Sarah Richardson, and Drex DeFord
In-depth interviews with healthcare CIOs, CISOs, and technology leaders. Bill Russell explores the decisions, strategies, and innovations shaping healthcare transformation.
Apr 29, 2026·Executive Interview
April 29, 2026: Bill Russell sits down with Jim Jacobs , President and CEO of MediQuant , to confront one of healthcare's most expensive and underappreciated problems: runaway application complexity. Jim makes the case that software rationalization isn't an IT to-do list item; it's a board-level imperative. With health systems carrying $60 million in unwanted software spend and cyber risks piling up in legacy systems that no one is maintaining, the urgency has never been higher. And with AI dema
Apr 27, 2026·Newsday
April 27, 2026: Drex DeFord and Bill Russell are back on Newsday, and fresh off the 229 Summit, they're not pulling punches. Healthcare IT has a demand problem. Too many projects, not enough capacity, and an industry that's chronically bad at saying no. From the 229 Summit's sharpest takeaways to the Salesforce headless CRM announcement, the vl.js hack, and why Bill thinks Claude Code's "genesis key" is about to change everything, this episode covers the stories that matter most right now. If yo
Apr 24, 2026·2 Minute Drill
While the industry debates frontier AI models and nation-state threats, hospitals are still getting hit by ransomware through the same doors they've always left open. Drex zooms out to what's actually happening on the ground: massive patch cycles creating downstream operational pressure, countries reconsidering their software dependencies, and CISOs quietly doubling down on fundamentals. MFA, identity management, tested backups, network segmentation. The HICP documents are free, the roadmap alre
Apr 20, 2026·Newsday
April 20, 2026: What happens when you layer AI onto broken processes without fixing them first? Angel Mena , MD, CMO of Symplr , joins Bill Russell, Drex DeFord, and Sarah Richardson on Newsday to answer that question with the kind of clinical candor only a practicing physician can bring. From ambient documentation to quality metrics to the credentialing chaos hiding inside every health system, this conversation exposes the gap between AI's promise and what healthcare leaders must do to close it
Apr 16, 2026·The 229 Podcast
April 16, 2026: Something big is changing at This Week Health, and it starts with this episode. Bill Russell sits down with Sarah Richardson to announce that Flourish, the beloved show Sarah has helmed since joining TWH, is joining the 229 Podcast. But this isn't a step back; it's a consolidation of purpose. Bill and Sarah unpack why simplifying to a single channel better serves the healthcare IT community, what listeners can expect going forward, and why the conversations that happened on Flour
Apr 15, 2026·2 Minute Drill
The Kim Wolf botnet was the most powerful ever built — 2 million compromised IoT devices, a record-breaking 31.4 terabit DDoS attack, and it had the FBI, Google, and Cloudflare stumped. Drex breaks down how those cheap, forgotten devices in patient waiting rooms and break rooms became weapons inside hospital networks, and why 25% of Infoblox's enterprise healthcare clients were already compromised. Then comes the wild part: a 22-year-old RIT undergrad named Benjamin cracked the whole operation —
Apr 13, 2026·Newsday
April 13, 2026: Jacob Hansen , Chief Product and Technology Officer at AvaSure , joins Bill, Drex, and Sarah on Newsday for a conversation about the data governance battles quietly reshaping AI. From who owns AI model improvements derived from a health system's environment to whether EHRs should have control over how that data is used, Jacob pulls no punches. The conversation also tackles the evolving CIO title, the future of computer science careers in an AI-driven world, and why nursing may be
Apr 9, 2026·2 Minute Drill
The window between vulnerability discovery and exploitation has collapsed — from 63 days in 2018 to negative. Now AI is changing the game entirely. Drex walks through how Anthropic's unreleased model Mythos autonomously found a critical zero-day in the Ghost CMS, wrote its own exploit, and extracted sensitive credentials in under two hours — all without a CVE ever existing. Add in two accidental Anthropic data leaks in the same week, and the story gets more complicated. For healthcare organizati
Apr 8, 2026·Executive Interview
April 8, 2026: Frank Duff , Chief Innovation Officer at Tidal Cyber , and one of the original architects of the Mitre ATT&CK framework, joins Drex DeFord on UnHack to expose an uncomfortable truth: most organizations are sitting on powerful security tools they've never fully turned on. Drawing from 18 years at Mitre and deep experience running ATT&CK evaluations, Frank explains how Tidal Cyber bridges the gap between what vendors build and what customers actually deploy. Squeezing more o
Apr 6, 2026·Newsday
April 6, 2026: The rules of warfare have changed, and health systems are caught in the middle. On this episode of Newsday, Sarah Richardson and Drex DeFord break down two stories that should be on every healthcare leader's radar: the IRGC's declaration that major tech companies are now legitimate combatants, and what the Stryker attack reveals about the fragility of the healthcare supply chain. From cloud co-location risk to vendor contract language, this conversation reframes what resilience pl
Apr 1, 2026·Executive Interview
April 1, 2026: James Winebrenner , CEO of Elisity , joins Drex DeFord to unpack one of healthcare cybersecurity's most persistent challenges, the sprawling, unseen attack surface hiding inside hospital networks. From unmanaged clinical devices to IoT systems running alongside regulated medical equipment, James breaks down how Elisity helps health systems move from visibility to control without re-engineering their networks. He also shares what The Pitt gets right about what really happens when a
Mar 31, 2026·2 Minute Drill
Drex makes the case for a role that doesn't exist yet but probably should: VP of Non-Human Resources. As AI agents multiply across health system environments, often deployed by vendors without oversight, the management infrastructure simply isn't keeping up. Agents have access, make judgment calls, and operate inside frameworks that affect patients and business operations, yet most have no job description, no onboarding, and no performance review. Drawing on signals from Harvard Business Review,
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