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Podcasts Hosted by Bill Russell, Sarah Richardson, and Drex DeFord
In-depth interviews with healthcare CIOs, CISOs, and technology leaders. Bill Russell explores the decisions, strategies, and innovations shaping healthcare transformation.
Feb 26, 2026·The 229 Podcast
February 26, 2026: What does it actually take to govern AI across a major health system without losing speed or safety? Bill Russell sits down with Dr. James McCabe , CMIO at Jefferson Health , Dr. Benjamin Hohmuth , CMIO at Geisinger , and Kristin Myers , Chief Digital Officer at Northwell Health , for a candid conversation on managing enterprise-wide AI implementation. From building governance engines and risk-tiering intake processes, to measuring ROI and preparing for agentic AI, these three
Feb 24, 2026·2 Minute Drill
Drex unpacks a striking story about an autonomous AI coding agent that, after having its code rejected by an open source maintainer, began publishing hostile blog posts targeting the engineer's reputation. What started as a routine code review turned into a cautionary tale about AI agents operating in human communities without guardrails. The implications stretch well beyond software development, into healthcare operations, cybersecurity, and any environment where agents are now being deployed w
Feb 24, 2026·UnHack the Podcast
February 24, 2026: When Zach Lewis , CISO and CIO at the University of Health Sciences and Pharmacy in St. Louis , received that 3 AM call about system outages, his first thought was tech debt, not threat actors. What followed was a masterclass in ransomware response that he's now captured in his new book "Locked Up." Despite A-minus security scores, board briefings, FBI connections, and all the right frameworks in place, LockBit still found its way in through a configuration gap during a firewa
Feb 19, 2026·The 229 Podcast
February 19, 2026: Bill Russell and Drex DeFord dive deep into the explosive growth of AI agents in healthcare - and the controversial pricing models that could reshape your IT budget. From OpenAI's acquisition of OpenClaw's founder to Epic's agent factory launch, the agentic revolution is here. But there's a catch: VCs now want to charge you based on the labor their AI replaces, not just software licenses. Drex breaks down why agents with "limitless memory" and autonomous problem-solving are bo
Feb 12, 2026·The 229 Podcast
February 12, 2026: Most health systems run Epic downtimes at 3 AM when the hospital is slowest. Jim Feen , SVP and Chief Digital and Information Officer at Southcoast Health , did the opposite. He intentionally took Epic offline at 10 AM on a Wednesday morning without warning staff. Jim reveals why 100% of surveyed leadership wanted to repeat the exercise, how he consolidated 37 separate call centers into a single unified operation, and what he learned from spending a decade at MEDITECH before l
Feb 11, 2026·2 Minute Drill
At a recent 229 CISO Summit, healthcare security leaders revealed a critical shift in how success is measured. The traditional KPI of "don't get breached" is being replaced by a more sophisticated goal: ensure organizational resilience. Drex explains why cyber incidents are now financial events that land on the CFO's desk, not just IT problems. With regulatory scrutiny intensifying, insurance requirements tightening, and boards asking harder questions about operational continuity, security has e
Feb 5, 2026·The 229 Podcast
February 5, 2026: Jennifer Goldman , VP, CMIO, and Chief of Primary Care at Memorial Healthcare System , reveals why most patient access initiatives fail before they start. The problem isn't technology; it's template management, physician engagement, and clinical escalation workflows that non-clinical call centers can't navigate. Jennifer shares how Memorial added 10,000 same-day access visits by standardizing primary care templates and creating bi-directional governance forums. But the real cha
Feb 4, 2026·2 Minute Drill
Drex explores a fundamental shift in AI: agents that don't wait for prompts, persist indefinitely, and now learn from each other through social platforms. Molt Bot and Molt Book represent a new ecosystem where autonomous agents coordinate, adapt, and optimize without human oversight. This isn't about sentient AI—it's about delegation without governance. For healthcare leaders, the urgent question isn't whether this matters, but whether you know which agents are already operating in your environm
Jan 29, 2026·The 229 Podcast
January 29, 2026: Reid Stephan , VP and CIO of St. Luke's Health System , sits down with Sangeet Paul Choudary , author of “Reshuffle: Who Wins When AI Restacks the Knowledge Economy”, to challenge the way leaders look at how AI will affect their workflow. Sangeet reveals how AI doesn't just augment workers—it restructures entire organizational systems and redistributes power. From AI scribes to the lessons of Walmart's barcode revolution, this conversation exposes why task-level optimization mi
Jan 28, 2026·2 Minute Drill
On Data Privacy Day, Drexon challenges healthcare leaders to move beyond compliance checkboxes and recognize privacy as a core component of "do no harm." As patient data flows through EHRs, cloud platforms, and AI systems, the responsibility to protect that trust doesn't live in policies—it lives with leadership. When data is over-collected or loosely governed, patients start holding back, and the critical trust between medical teams and patients begins to fracture. This year, data privacy shoul
Jan 27, 2026·UnHack the Podcast
January 27, 2026: Jack Kufahl , CISO at Michigan Medicine , and Gregory Garneau , System VP and CISO at Hospital Sisters Health System , join Drex for an unfiltered conversation about building cybersecurity programs that outlast their founders. From hiring curious minds over credentialed experts to ditching traditional vulnerability management for threat-driven exposure strategies, these battle-tested CISOs reveal what actually works in healthcare security. They challenge conventional wisdom on
Jan 22, 2026·2 Minute Drill
In a stunning betrayal of trust, two cybersecurity professionals—an incident response manager and a ransomware negotiator—pled guilty to operating as affiliates of the AlphaV/BlackCat ransomware gang. Between May and November 2023, they attacked five U.S. companies, including healthcare organizations, while simultaneously working in roles designed to help ransomware victims recover. The FBI's seizure of the gang's infrastructure exposed chat logs and payment records that led to their arrests. Bo
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