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January 22, 2026

Mass General Study: Frequent AI Chatbot Use Linked to Higher Depression in Adults

MedPage Today
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Contributed by: Kate Gamble
Summary
A recent survey study led by Dr. Roy H. Perlis from Massachusetts General Hospital found a significant association between regular use of generative AI chatbots and increased depressive symptoms, particularly among individuals aged 25 to 64. The research indicated that daily or frequent use of AI for personal reasons correlated with higher levels of depression, as measured by the Patient Health Questionnaire. These findings suggest a need for healthcare professionals to monitor mental health outcomes in patients utilizing AI tools, especially in younger adults. Further longitudinal studies are necessary to explore the potential causal relationship between AI use and mood changes.

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